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human breast cancer tissue arrays  (Biomax Inc)
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Biomax Inc human breast cancer tissue arrays
Figure 6. YB-1 and DACH1 expression is inversely correlated in <t>human</t> luminal A and basal genetic subtypes. The mRNA abundance for YB-1 and DACH1 in basal <t>breast</t> <t>cancer</t> cell lines (A) and human breast cancer cell line (B). C, IHC for DACH1 and YB-1 in normal breast and basal breast cancer (B) mRNA for YB-1 and DACH1 in basal-like breast cancer cell lines (A) and human breast cancer cell lines (B). D, a combined breast cancer microarray data set assigning the five breast cancer genetic expression subtypes are shown as a heat map. The ESR1, EGFR (ERBB2), and progesterone receptor (PGR) are shown together with YB-1 and DACH1 expression. E–I, normalized DACH1 expression plotted versus normalized YB-1 expression level reveals the inverse relationship between DACH1 and YB-1 expression in luminal A and basal genetic subtype (red circle).
Human Breast Cancer Tissue Arrays, supplied by Biomax Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Figure 6. YB-1 and DACH1 expression is inversely correlated in human luminal A and basal genetic subtypes. The mRNA abundance for YB-1 and DACH1 in basal breast cancer cell lines (A) and human breast cancer cell line (B). C, IHC for DACH1 and YB-1 in normal breast and basal breast cancer (B) mRNA for YB-1 and DACH1 in basal-like breast cancer cell lines (A) and human breast cancer cell lines (B). D, a combined breast cancer microarray data set assigning the five breast cancer genetic expression subtypes are shown as a heat map. The ESR1, EGFR (ERBB2), and progesterone receptor (PGR) are shown together with YB-1 and DACH1 expression. E–I, normalized DACH1 expression plotted versus normalized YB-1 expression level reveals the inverse relationship between DACH1 and YB-1 expression in luminal A and basal genetic subtype (red circle).

Journal: Cancer Research

Article Title: Cell Fate Factor DACH1 Represses YB-1–Mediated Oncogenic Transcription and Translation

doi: 10.1158/0008-5472.can-13-2466

Figure Lengend Snippet: Figure 6. YB-1 and DACH1 expression is inversely correlated in human luminal A and basal genetic subtypes. The mRNA abundance for YB-1 and DACH1 in basal breast cancer cell lines (A) and human breast cancer cell line (B). C, IHC for DACH1 and YB-1 in normal breast and basal breast cancer (B) mRNA for YB-1 and DACH1 in basal-like breast cancer cell lines (A) and human breast cancer cell lines (B). D, a combined breast cancer microarray data set assigning the five breast cancer genetic expression subtypes are shown as a heat map. The ESR1, EGFR (ERBB2), and progesterone receptor (PGR) are shown together with YB-1 and DACH1 expression. E–I, normalized DACH1 expression plotted versus normalized YB-1 expression level reveals the inverse relationship between DACH1 and YB-1 expression in luminal A and basal genetic subtype (red circle).

Article Snippet: Human breast cancer tissue arrays were from Biomax.

Techniques: Expressing, Microarray